https://www.ceesdekker.net Secrets

https://www.ceesdekker.net Secrets

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Nanotechnology gives A selection of alternatives to add to biology. Here I will current illustrations exactly where nanofabrication – the chance to make confined constructions with dimensions at will – is utilised to look at the biophysics of solitary molecules and cells. I will current some examples from our lab:

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Within the very same time, the group of Paul McEuen, who was then centered for the University of California, Berkeley, confirmed related final results on ropes of bundled nanotubes. According to the wrapping angle, nanotubes can come in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard University independently verified utilizing scanning tunnelling spectroscopy experiments.

Deposition and atomic pressure microscopy of specific phthalocyanine polymers involving nanofabricated electrodes

2010, created a fresh way (‘wedging transfer’) to control nanostructures; initially report of DNA translocation as a result of graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into strong-state nanopores

Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

We use nanofabricated microfluidic constructions to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental purpose of spatial confinement for the molecular and mobile degree. Our tasks contain the following:

He also uncovered time to write down quite a few publications, send out Nearly forty ceesdekker.net thousand tweets and direct A prosperous analysis team at Delft University of Technological innovation. ‘It doesn’t feel like operate’, he says. ‘I’m just terribly curious.’

In 1993, as being a younger and keen affiliate professor at Delft College of Technologies, I'd to begin with focused the study initiatives of my team on measuring the electrical conductance of only one conducting-polymer molecule. Within two a long time, we experienced made a tool in which just one wire of a phthalocyaninepolysiloxane polymer was linked involving two intently spaced metallic nanoelectrodes.

‘The fantastically subtle way in which features in character perform by no means ceases to amaze me. If we solve the puzzle of how everyday living arrived into becoming, I expect that my amazement at the complexity of generation could have elevated and with it my awe for the greatness of your Creator.’

Testing pseudotopological and nontopological types for SMC-pushed DNA loop extrusion against roadblock-traversal experiments

Afterwards we spoke yet again briefly because Dekker felt that our discussion of his faith swiftly grew to become purely philosophical, While In addition it concretely helps him in his function.

Let’s very first seem back again at this time when you decided to change your focus from superconductivity and nanotubes to biology at the end of the 1990s.

2004, discovery of latest physics in translocation of DNA through nanopores; initially experimental research of ions conduction in nanofluidic channels; to start with electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; initial biophysics characterization of your mechanical Homes of double-stranded RNA; and first solitary-molecule study of DNA translocation by a restriction-modification enzyme.